Lisinopril (Prinivil, Zestril) is an antihypertensive agent that belongs to a class of drugs known as angiotensin-converting enzyme inhibitors (ACE-inhibitors). Lisinopril is used in the treatment of high blood pressure, kidney disease and heart failure.
| Generic name | Lisinopril |
| Brand name | Prinivil, Zestril |
| Drug class | Angiotensin-converting enzyme inhibitors |
| Drug group | Antihypertensive |
| Black box warnings | Pregnancy |
It acts by preventing the conversion of angiotensin I to angiotensin II (a potent vasoconstrictor), and thus, decreases blood pressure.
Lisinopril can cause various adverse reactions, most commonly rash and persistent dry cough. To minimize these effects a reduction of dosage may necessary.
- Rash
- Persistent dry cough
- Headache
- Dizziness
- Postural hypotension
- Hyperkalemia (high potassium level in the blood)
- Nephrotoxicity
- Chest discomfort
- Upper respiratory infection
- Fatigue
- Abdominal pain
- Vomiting
- Nausea
- Diarrhea
- Hallucination
- Changes in mood
- Angioedema
- Liver failure
- Palpitations (a suddenly noticeable heartbeat)
- Tachycardia
- Insomnia
- Paresthesia (prickling sensation)
- Muscle cramps
- Gynecomastia (abnormal enlargement of breasts in males)
- Bone marrow depression
- Autoimmune disorders
- Mouth ulcers
- Sore throat
- Fever
- Breathing difficulty
- Excessive hypotension (occur in patients with heart failure)
- Swelling of face and lips (Angioedema)
- Hyperkalemia
- Agranulocytosis and neutropenia (may be noted in patients with collagen vascular disease)
- Nephrotic syndrome (might be noted in patients with a history of renal disease)
1. Kizior, R.J. and Hodgson, B.B. (2018). Saunders nursing drug handbook 2019. Philadelphia: Saunders.
2. British Medical Association (2015). British Medical Association new guide to medicine & drugs. London: Dorling Kindersley.
3. Joint formulary committee, BNF 80 (The British National Formulary), 80th Revised edition, Pharmaceutical Press, London, United Kingdom, [2020].
4. Kolesar, J.M. (2016). Mcgraw-hill’s 2018/2019 top 300 pharmacy drug cards.
Lisinopril is an ACE inhibitor that is used in the treatment of high blood pressure, kidney disease and heart failure. It is available as tablets and oral solutions.
Chronic kidney disease (CKD) is a disease in which irreversible damage to the kidneys leads to a reduction in kidney function. CKD has 5 stages and many complications.
Hyperemia is buildup of blood within vessels of an organ. Hyperemia is divided into two types: Active and passive, what causes active hyperemia?
This article focuses on the side effects of the drug as well as lisinopril warnings. Click here to read about the most common, common, and rare side effects of this medication.
Dosage guide of Lisinopril: Click to read about the dose for your specific condition and age group.
Subscribe to our email lists and upgrade your life into a healthier and happier one.
SubscribeSign up for our newsletter(s) and receive healthy and scientific content to have a healthier life.
Choose Newsletter(s)Follow Medical Hex on social media platforms to be informed about latest health news and health-related scientific concepts.
A place you can find correct medical advice and information on health conditions as well as medical scientific articles. Our aim is to improve the health of human race by increasing health literacy through providing science-based content about health conditions.
©2022 Medical Hex. All Rights Reserved.