The two kidneys are bean-shaped organs located on the posterior abdominal wall outside the peritoneal cavity, one on either side of the vertebral column at the level of the T12 to L1 vertebrae. The right kidney is slightly lower than the left kidney because of the large size of the right liver lobe. The kidney is enclosed by a thick, fibrous capsule that protects its delicate internal structures.
The kidneys are reddish-brown in color. adult human kidney weighs about 150 grams and is about the size of a clenched fist. It measures approximately 10 cm in length, 5 cm in width, and 2.5 cm in thickness.
The medial side of each kidney includes an indented area called the renal hilum, a vertical cleft present on the concave medial margin through which the renal artery and vein, lymphatics, nerve supply, and ureter pass. It is the entrance to space inside the kidney called the renal sinus. Thus, the renal sinus is occupied by the renal pelvis, calyces, veins, nerves, and a variable amount of fat.
If the kidney is bisected from top to bottom, the outer cortex and the inner medulla regions are the two main regions that can be visualized. The medulla is divided into 8 to 10 cone-shaped mass of tissue called renal pyramids. The renal pyramids are triangular regions of renal tissue, which are 4–14 in number and divided from each other by cortical renal columns. Each pyramid has a base that is oriented towards the cortex, and an apex (or renal papilla) that protrudes into the renal pelvis and fits into a minor calyx.
The renal pelvis is a flattened funnel-shaped continuation of the upper end of the ureter. the outer border of the pelvis is divided into two (or three) parts, called major calyxes, which extend down and divide into several minor calyxes. The end of each minor calyx is shaped like a cup that collects urine from the tubes of each papilla. The walls of the calyces, pelvis, and ureter contain contractile elements that propel the urine to the bladder, where the urine is stored until it is emptied by micturition.
The renal cortex is the outer tissue layer of the kidney, dark and granular in appearance. The renal cortex can be divided into two sections which are continuous with each other:
1. K SEMBULINGAM AND PREMA SEMBULINGAM, Essentials of Medical Physiology, Sixth Edition, New Delhi, Panama City, London, Dhaka, Kathmandu, JAYPEE BROTHERS MEDICAL PUBLISHERS (P) LTD, [2012]
2. INDU KHURANA AND ARUSHI KHURANA, Textbook of Medical Physiology, 2nd Edition, India, Elsevier India, [December 1, 2015]
3. JOHN FEEHALLY, JÜRGEN FLOEGE, MARCELLO TONELLI, RICHARD J. JOHNSON, Comprehensive Clinical Nephrology, Sixth Edition, Edinburgh, London, New York, Oxford, Philadelphia, StLouis, Sydney, Elsevier, [September 11, 2018]
4. VALERIE C. SCANLON, TINA SANDERS, Essentials of Anatomy and Physiology, fifth edition, New York, F. A. Davis Company, [January 1, 2006]
5. KIM E. BARRETT, SUSAN M. BARMAN, HEDDWEN L. BROOKS, JASON YUAN, Ganong's Review of Medical Physiology, 26th edition, New York, Chicago, San Francisco, Athens, London, Madrid, Mexico City, Milan, New Delhi, Singapore, Sydney, Toronto, Mc Graw Hill Education, [January 29, 2019]
6. ANNE WAUGH, ALLISON GRANT, Ross and Wilson ANATOMY and PHYSIOLOGY in Health and Illness, 11th edition, Edinburgh, London, New York, Oxford, Philadelphia, St Louis Sydney, Toronto, Churchill Livingstone, [September 7, 2010]
7. GUYTON AND HALL, Textbook of Medical Physiology, 12th edition, Jackson, Mississippi, University of Mississippi Medical Center, [2011]
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