2. Indications & dosages of ophthalmic ofloxacin
Ofloxacin eye drops are used to treat eye infections. The drug belongs to a class known as fluoroquinolones, which are used to treat bacterial infections. Ofloxacin can only treat eye infections caused by bacteria, it will be ineffective in treatment of other kinds of eye infection.
After applying the eye drop, make sure to apply a light finger pressure to the lacrimal sac for 1 minute. This will prevent draining out of the medication through this sac.
Conjunctivitis:
when caused by (Staphylococcus aureus, S. epidermidis, Streptococcus pneumonia, Enterobacter cloacae, Hemophilus influenzae, Proteus mirabilis, and Pseudomonas aeruginosa).
Adults and children over the age of one: 1 or 2 drops in the conjunctival sac every 2 to 4 hours while the patient is awake for the first 2 days, then four times a day for up to 5 days.
Bacterial corneal ulcer:
When caused by (S. aureus, S. epidermidis, S. pneumoniae, P. aeruginosa, Serratia marcescens, and Propionibacterium acnes).
Adults and children over the age of one should administer 1 or 2 drops every 30 minutes while awake, and 1 or 2 drops (4 and 6 hours after going to bed) on days 1 and 2. 1 or 2 drops hourly while the patient is awake on day 3; continue for 4 to 6 days. Then, 1 or 2 drops four times a day for 3 days, or until cured.
| Acute myocardial infarction (a risk factor for QT interval prolongation). | |
| Bradycardia (a risk factor for QT interval prolongation). | |
| Congenital long QT syndrome (a risk factor for QT interval prolongation). | |
| Electrolyte disturbances (a risk factor for QT interval prolongation). | |
| Heart failure with reduced left ventricular ejection fraction (a risk factor for QT interval prolongation). | |
| History of psychiatric illness. | |
| History of symptomatic arrhythmias (a risk factor for QT interval prolongation). |
(Ophthalmic)
- Contraindicated in patients who are hypersensitive to the drug or other fluoroquinolones, as well as in women who are breastfeeding.
| Transient ocular burning or discomfort | |
| Chemical conjunctivitis or keratitis | |
| Eye dryness | |
| Eye pain | |
| Itching | |
| Lacrimation | |
| Periocular or facial edema | |
| Photophobia | |
| Redness | |
| Stinging |
-None significant.
1.Joint Formulary Committee (2019). BNF 78: September 2019-March 2020. 78th ed. London: Pharmaceutical Press.
2.Williams and Wolters Kluwer Health (2012). Nursing 2012 drug handbook. Philadelphia, Pa.: Wolters Kluwer Health/Lippincott Williams & Wilkins.
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